Identifying functional effects of noncoding variants is a major challenge in human genetics. To predict the noncoding-variant effects de novo from sequence, we ...

Premise of research. The transition from herbaceous annual to woody perennial has occurred numerous times during angiosperm evolution, but the suite of genetic changes that accompanies this life ...

Superimposed on the genetic sequences coding for amino acids is a second genetic code. This second genetic code, which makes use of dual-use codons, or duons, specifies how genes are controlled. The ...