Solid tumors are highly dependent upon angiogenesis for their survival. However, in tumors such as pancreatic and hepatobiliary carcinomas, the newly formed vasculature is often immature and unable to ...

Over the past 20 years the baculovirus–insect cell expression system has become one of the most widely used systems for routine production of recombinant proteins 1,2,3,4,5,6. A number of ...

In biopharmaceutical manufacturing, the development of an expression system that stably produces high levels of desired recombinant protein can be a time consuming and resource-intensive process. In ...

Despite the undeniable ability of viral vectors to deliver genetic payloads, and despite the incredible promise of this approach to treat a vast variety of diseases—including metabolic, cardiovascular ...