The nucleus is guarded by a highly secure door, the so-called nuclear pore, that controls the transport of substances from the cytoplasm to the cell nucleus and back. A research group has now shown ...

Most current approaches rely on adding nuclear localization signal (NLS) motifs to the ends of Cas9 to facilitate nuclear entry. However, this method is inefficient, and much of the Cas9 that is ...

Plankton are the invisible engines of life on Earth, producing much of the planet's oxygen and forming the foundation of the ...

For numerous individuals with schizophrenia, living with the condition involves challenges, not only related to hallucinations or delusions, but also due to subtler difficulties, such as problems ...

A study takes a closer look at a virus that causes tumors in monkeys called SV40. The unique way it infects a cell's nucleus could underpin its ability to cause cancer. Viruses are tiny packets of ...

A team of Yale researchers discovered how a protein called Ndc1 coordinates nuclear pore and envelope assembly after cell division, an important component of understanding how cell nuclei change in ...

Cancer cells are subjected to high mechanical pressure that leads to a rupture of the nuclear envelope when migrating through narrow tissue structures, as in the case of metastasis. DNA would normally ...

The most dangerous animal in the world just got easier to study—and perhaps defeat one day. Researchers from Rockefeller ...

A newly discovered nuclear role for HSL reveals how imbalances in its location within fat cells may contribute to both ...